1B8X

GLUTATHIONE S-TRANSFERASE FUSED WITH THE NUCLEAR MATRIX TARGETING SIGNAL OF THE TRANSCRIPTION FACTOR AML-1

1B8X の概要

• エントリーDOI: 10.2210/pdb1b8x/pdb
• 分子名称: PROTEIN (AML-1B) (1 entity in total)
• 機能のキーワード: nuclear matrix targeting signal protein, signal protein
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 32124.12

構造登録者

Tang, L.,Guo, B.,Van Wijnen, A.J.,Lian, J.B.,Stein, J.L.,Stein, G.S.,Zhou, G.W. (登録日: 1999-02-03, 公開日: 1999-04-12, 最終更新日: 2023-08-09)

主引用文献

Tang, L.,Guo, B.,van Wijnen, A.J.,Lian, J.B.,Stein, J.L.,Stein, G.S.,Zhou, G.W.
Preliminary crystallographic study of glutathione S-transferase fused with the nuclear matrix targeting signal of the transcription factor AML-1/CBF-alpha2.
J.Struct.Biol., 123:83-85, 1998

PubMed Abstract: A glutathione S-transferase fused with the nuclear matrix targeting signal (GST-NMTS) of AML-1/CBF-alpha2 has been crystallized by the vapor diffusion method using polyethylene glycol (PEG) as the precipitant. The NMTS is a 31-amino-acid signal peptide that can target the AML-1/CBF-alpha2 protein to the nuclear matrix. The crystal belongs to tetragonal space group P43212 with unit cell dimensions a = b = 93.4 A, c = 57.6 A. There is one GST-fusion protein per asymmetric unit. Crystals diffracted to at least 2.7 A and are appropriate for structure determination.

PubMed: 9774548
DOI: 10.1006/jsbi.1998.4016

実験手法

X-RAY DIFFRACTION (2.7 Å)