1B8C

PARVALBUMIN

1B8C の概要

• エントリーDOI: 10.2210/pdb1b8c/pdb
• 分子名称: PROTEIN (PARVALBUMIN), MAGNESIUM ION (3 entities in total)
• 機能のキーワード: calcium binding protein, ef-hand proteins, parvalbumin, calcium-binding
• 由来する生物種: Cyprinus carpio (common carp)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 22912.19

構造登録者

Cates, M.S.,Berry, M.B.,Ho, E.L.,Li, Q.,Potter, J.D.,Phillips Jr., G.N. (登録日: 1999-01-29, 公開日: 1999-02-02, 最終更新日: 2023-08-09)

主引用文献

Cates, M.S.,Berry, M.B.,Ho, E.L.,Li, Q.,Potter, J.D.,Phillips Jr., G.N.
Metal-ion affinity and specificity in EF-hand proteins: coordination geometry and domain plasticity in parvalbumin.
Structure Fold.Des., 7:1269-1278, 1999

PubMed Abstract: The EF-hand family is a large set of Ca(2+)-binding proteins that contain characteristic helix-loop-helix binding motifs that are highly conserved in sequence. Members of this family include parvalbumin and many prominent regulatory proteins such as calmodulin and troponin C. EF-hand proteins are involved in a variety of physiological processes including cell-cycle regulation, second messenger production, muscle contraction, microtubule organization and vision.

PubMed: 10545326
DOI: 10.1016/S0969-2126(00)80060-X

実験手法

X-RAY DIFFRACTION (2 Å)