1B48

CRYSTAL STRUCTURE OF MGSTA4-4 IN COMPLEX WITH GSH CONJUGATE OF 4-HYDROXYNONENAL IN ONE SUBUNIT AND GSH IN THE OTHER: EVIDENCE OF SIGNALING ACROSS DIMER INTERFACE IN MGSTA4-4

1B48 の概要

• エントリーDOI: 10.2210/pdb1b48/pdb
• 分子名称: PROTEIN (GLUTATHIONE S-TRANSFERASE), 4-S-GLUTATHIONYL-5-PENTYL-TETRAHYDRO-FURAN-2-OL, GLUTATHIONE, ... (4 entities in total)
• 機能のキーワード: glutathione s-transferase, gst, subunit cooperativity, transferase
• 由来する生物種: Mus musculus (house mouse)
• 細胞内の位置: Cytoplasm: P24472
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 51724.32

構造登録者

Xiao, B.,Zimniak, P.,Ji, X. (登録日: 1999-01-06, 公開日: 1999-09-29, 最終更新日: 2023-08-30)

• 主引用文献: Xiao, B.,Singh, S.P.,Nanduri, B.,Awasthi, Y.C.,Zimniak, P.,Ji, X.; Crystal structure of a murine glutathione S-transferase in complex with a glutathione conjugate of 4-hydroxynon-2-enal in one subunit and glutathione in the other: evidence of signaling across the dimer interface.; Biochemistry, 38:11887-11894, 1999; PubMed: 10508391; DOI: 10.1021/bi990468i

実験手法

X-RAY DIFFRACTION (2.6 Å)