1B3D
STROMELYSIN-1
Summary for 1B3D
| Entry DOI | 10.2210/pdb1b3d/pdb |
| Descriptor | STROMELYSIN-1, ZINC ION, CALCIUM ION, ... (5 entities in total) |
| Functional Keywords | stromelysin, matrix metalloproteinase, osteoarthritis, protein crystal structure, structure-based drug design, protein, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Homo sapiens (human) |
| Cellular location | Secreted, extracellular space, extracellular matrix (Probable): P08254 |
| Total number of polymer chains | 2 |
| Total formula weight | 39709.58 |
| Authors | Chen, L.,Rydel, T.J.,Dunaway, C.M.,Pikul, S.,Dunham, K.M.,Gu, F.,Barnett, B.L. (deposition date: 1998-12-09, release date: 1999-12-10, Last modification date: 2023-12-27) |
| Primary citation | Chen, L.,Rydel, T.J.,Gu, F.,Dunaway, C.M.,Pikul, S.,Dunham, K.M.,Barnett, B.L. Crystal structure of the stromelysin catalytic domain at 2.0 A resolution: inhibitor-induced conformational changes. J.Mol.Biol., 293:545-557, 1999 Cited by PubMed: 10543949DOI: 10.1006/jmbi.1999.3147 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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