1B3D

STROMELYSIN-1

1B3D の概要

• エントリーDOI: 10.2210/pdb1b3d/pdb
• 分子名称: STROMELYSIN-1, ZINC ION, CALCIUM ION, ... (5 entities in total)
• 機能のキーワード: stromelysin, matrix metalloproteinase, osteoarthritis, protein crystal structure, structure-based drug design, protein, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Secreted, extracellular space, extracellular matrix (Probable): P08254
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 39709.58

構造登録者

Chen, L.,Rydel, T.J.,Dunaway, C.M.,Pikul, S.,Dunham, K.M.,Gu, F.,Barnett, B.L. (登録日: 1998-12-09, 公開日: 1999-12-10, 最終更新日: 2023-12-27)

• 主引用文献: Chen, L.,Rydel, T.J.,Gu, F.,Dunaway, C.M.,Pikul, S.,Dunham, K.M.,Barnett, B.L.; Crystal structure of the stromelysin catalytic domain at 2.0 A resolution: inhibitor-induced conformational changes.; J.Mol.Biol., 293:545-557, 1999; PubMed: 10543949; DOI: 10.1006/jmbi.1999.3147

実験手法

X-RAY DIFFRACTION (2.3 Å)