1B2W
COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF A HUMANIZED AND A CHIMERIC FAB OF AN ANTI-GAMMA-INTERFERON ANTIBODY
1B2W の概要
エントリーDOI | 10.2210/pdb1b2w/pdb |
分子名称 | PROTEIN (ANTIBODY (LIGHT CHAIN)), PROTEIN (ANTIBODY (HEAVY CHAIN)) (2 entities in total) |
機能のキーワード | antibody engineering, humanized and chimeric antibody, fab, three-dimensional strycture, gamma-interferon, immune system |
由来する生物種 | Mus musculus, Homo sapiens 詳細 |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 47231.68 |
構造登録者 | Fan, Z.,Shan, L.,Goldsteen, B.Z.,Guddat, L.W.,Thakur, A.,Landolfi, N.F.,Co, M.S.,Vasquez, M.,Queen, C.,Ramsland, P.A.,Edmundson, A.B. (登録日: 1998-12-01, 公開日: 1999-05-06, 最終更新日: 2023-08-09) |
主引用文献 | Fan, Z.C.,Shan, L.,Goldsteen, B.Z.,Guddat, L.W.,Thakur, A.,Landolfi, N.F.,Co, M.S.,Vasquez, M.,Queen, C.,Ramsland, P.A.,Edmundson, A.B. Comparison of the three-dimensional structures of a humanized and a chimeric Fab of an anti-gamma-interferon antibody. J.Mol.Recog., 12:19-32, 1999 Cited by PubMed: 10398393DOI: 10.1002/(SICI)1099-1352(199901/02)12:1<19::AID-JMR445>3.3.CO;2-P 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.9 Å) |
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