1B2W

COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF A HUMANIZED AND A CHIMERIC FAB OF AN ANTI-GAMMA-INTERFERON ANTIBODY

1B2W の概要

• エントリーDOI: 10.2210/pdb1b2w/pdb
• 分子名称: PROTEIN (ANTIBODY (LIGHT CHAIN)), PROTEIN (ANTIBODY (HEAVY CHAIN)) (2 entities in total)
• 機能のキーワード: antibody engineering, humanized and chimeric antibody, fab, three-dimensional strycture, gamma-interferon, immune system
• 由来する生物種: Mus musculus, Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 47231.68

構造登録者

Fan, Z.,Shan, L.,Goldsteen, B.Z.,Guddat, L.W.,Thakur, A.,Landolfi, N.F.,Co, M.S.,Vasquez, M.,Queen, C.,Ramsland, P.A.,Edmundson, A.B. (登録日: 1998-12-01, 公開日: 1999-05-06, 最終更新日: 2023-08-09)

• 主引用文献: Fan, Z.C.,Shan, L.,Goldsteen, B.Z.,Guddat, L.W.,Thakur, A.,Landolfi, N.F.,Co, M.S.,Vasquez, M.,Queen, C.,Ramsland, P.A.,Edmundson, A.B.; Comparison of the three-dimensional structures of a humanized and a chimeric Fab of an anti-gamma-interferon antibody.; J.Mol.Recog., 12:19-32, 1999; PubMed: 10398393; DOI: 10.1002/(SICI)1099-1352(199901/02)12:1<19::AID-JMR445>3.3.CO;2-P

実験手法

X-RAY DIFFRACTION (2.9 Å)