The crystal structure of phosphoglucose isomerase-an enzyme with autocrine motility factor activity in tumor cells

Summary for 1B0Z

DescriptorPROTEIN (PHOSPHOGLUCOSE ISOMERASE) (2 entities in total)
Functional Keywordsphosphoglucose isomerase, autocrinefactor, neuroleukin, crystallography motility, isomerase
Biological sourceGeobacillus stearothermophilus
Cellular locationCytoplasm P13376
Total number of polymer chains1
Total molecular weight50202.76
Sun, Y.-J.,Chou, C.-C.,Chen, W.-S.,Meng, M.,Hsiao, C.-D. (deposition date: 1998-11-15, release date: 1999-11-10, Last modification date: 2011-07-13)
Primary citation
Chou, C.-C.,Sun, Y.-J.,Meng, M.,Hsiao, C.-D.
The crystal structure of phosphoglucose isomerase/autocrine motility factor/neuroleukin complexed with its carbohydrate phosphate inhibitors suggests its substrate/receptor recognition
J.Biol.Chem., 275:23154-23160, 2000
PubMed: 10770936 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M002017200
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.266180.9%15.6%0.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution