1B07

CRK SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR

1B07 の概要

• エントリーDOI: 10.2210/pdb1b07/pdb
• 分子名称: PROTEIN (PROTO-ONCOGENE CRK (CRK)), PROTEIN (SH3 PEPTOID INHIBITOR), PHENYLETHANE, ... (4 entities in total)
• 機能のキーワード: sh3 domain, inhibitors, peptoids, protein-protein recognition, proline-rich motifs, signal transduction
• 由来する生物種: Mus musculus (house mouse)
• 細胞内の位置: Cytoplasm (By similarity): Q64010
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 9319.37

構造登録者

Nguyen, J.T.,Turck, C.W.,Cohen, F.E.,Zuckermann, R.N.,Lim, W.A. (登録日: 1998-11-17, 公開日: 1999-01-06, 最終更新日: 2023-08-09)

• 主引用文献: Nguyen, J.T.,Turck, C.W.,Cohen, F.E.,Zuckermann, R.N.,Lim, W.A.; Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors.; Science, 282:2088-2092, 1998; PubMed: 9851931; DOI: 10.1126/science.282.5396.2088

実験手法

X-RAY DIFFRACTION (2.5 Å)