1AZM

DRUG-PROTEIN INTERACTIONS: STRUCTURE OF SULFONAMIDE DRUG COMPLEXED WITH HUMAN CARBONIC ANHYDRASE I

Summary for 1AZM

Entry DOI	10.2210/pdb1azm/pdb
Descriptor	CARBONIC ANHYDRASE I, ZINC ION, 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, ... (4 entities in total)
Functional Keywords	protein-drug interactions, oxo-acid lyase, sulfonamides, lyase(oxo-acid)
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P00915
Total number of polymer chains	1
Total formula weight	29062.64
Authors	Chakravarty, S.,Kannan, K.K. (deposition date: 1993-11-28, release date: 1994-04-30, Last modification date: 2024-02-07)
Primary citation	Chakravarty, S.,Kannan, K.K. Drug-protein interactions. Refined structures of three sulfonamide drug complexes of human carbonic anhydrase I enzyme. J.Mol.Biol., 243:298-309, 1994 Cited by PubMed: 7932756 DOI: 10.1006/jmbi.1994.1655 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation