1AYF

BOVINE ADRENODOXIN (OXIDIZED)

Summary for 1AYF

• Entry DOI: 10.2210/pdb1ayf/pdb
• Descriptor: ADRENODOXIN, FE2/S2 (INORGANIC) CLUSTER, GLYCEROL, ... (4 entities in total)
• Functional Keywords: [2fe-2s]ferredoxin, adrenodoxin, electron transport
• Biological source: Bos taurus (cattle)
• Cellular location: Mitochondrion matrix: P00257
• Total number of polymer chains: 2
• Total formula weight: 23766.14

Authors

Mueller, A.,Mueller, J.J.,Heinemann, U. (deposition date: 1997-11-03, release date: 1998-12-30, Last modification date: 2024-02-07)

Primary citation

Muller, A.,Muller, J.J.,Muller, Y.A.,Uhlmann, H.,Bernhardt, R.,Heinemann, U.
New aspects of electron transfer revealed by the crystal structure of a truncated bovine adrenodoxin, Adx(4-108).
Structure, 6:269-280, 1998

PubMed Abstract: Adrenodoxin (Adx) is a [2Fe-2S] ferredoxin involved in steroid hormone biosynthesis in the adrenal gland mitochondrial matrix of mammals. Adx is a small soluble protein that transfers electrons from adrenodoxin reductase (AR) to different cytochrome P450 isoforms where they are consumed in hydroxylation reactions. A crystallographic study of Adx is expected to reveal the structural basis for an important electron transfer reaction mediated by a vertebrate [2Fe-2S] ferredoxin.

PubMed: 9551550
DOI: 10.1016/S0969-2126(98)00031-8

Experimental method

X-RAY DIFFRACTION (1.85 Å)