1AYF

BOVINE ADRENODOXIN (OXIDIZED)

1AYF の概要

• エントリーDOI: 10.2210/pdb1ayf/pdb
• 分子名称: ADRENODOXIN, FE2/S2 (INORGANIC) CLUSTER, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: [2fe-2s]ferredoxin, adrenodoxin, electron transport
• 由来する生物種: Bos taurus (cattle)
• 細胞内の位置: Mitochondrion matrix: P00257
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 23766.14

構造登録者

Mueller, A.,Mueller, J.J.,Heinemann, U. (登録日: 1997-11-03, 公開日: 1998-12-30, 最終更新日: 2024-02-07)

主引用文献

Muller, A.,Muller, J.J.,Muller, Y.A.,Uhlmann, H.,Bernhardt, R.,Heinemann, U.
New aspects of electron transfer revealed by the crystal structure of a truncated bovine adrenodoxin, Adx(4-108).
Structure, 6:269-280, 1998

PubMed Abstract: Adrenodoxin (Adx) is a [2Fe-2S] ferredoxin involved in steroid hormone biosynthesis in the adrenal gland mitochondrial matrix of mammals. Adx is a small soluble protein that transfers electrons from adrenodoxin reductase (AR) to different cytochrome P450 isoforms where they are consumed in hydroxylation reactions. A crystallographic study of Adx is expected to reveal the structural basis for an important electron transfer reaction mediated by a vertebrate [2Fe-2S] ferredoxin.

PubMed: 9551550
DOI: 10.1016/S0969-2126(98)00031-8

実験手法

X-RAY DIFFRACTION (1.85 Å)