1AXM

HEPARIN-LINKED BIOLOGICALLY-ACTIVE DIMER OF FIBROBLAST GROWTH FACTOR

1AXM の概要

• エントリーDOI: 10.2210/pdb1axm/pdb
• 分子名称: ACIDIC FIBROBLAST GROWTH FACTOR, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, ... (4 entities in total)
• 機能のキーワード: human acidic fibroblast growth factor, heparin decasaccharide, growth factor
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 96434.20

構造登録者

DiGabriele, A.D.,Lax, I.,Chen, D.I.,Svahn, C.M.,Jaye, M.,Schlessinger, J.,Hendrickson, W.A. (登録日: 1997-10-16, 公開日: 1998-04-22, 最終更新日: 2023-08-02)

• 主引用文献: DiGabriele, A.D.,Lax, I.,Chen, D.I.,Svahn, C.M.,Jaye, M.,Schlessinger, J.,Hendrickson, W.A.; Structure of a heparin-linked biologically active dimer of fibroblast growth factor.; Nature, 393:812-817, 1998; PubMed: 9655399; DOI: 10.1038/31741

実験手法

X-RAY DIFFRACTION (3 Å)