1AV6

VACCINIA METHYLTRANSFERASE VP39 COMPLEXED WITH M7G CAPPED RNA HEXAMER AND S-ADENOSYLHOMOCYSTEINE

Summary for 1AV6

• Entry DOI: 10.2210/pdb1av6/pdb
• Descriptor: RNA (5'-R(*GP*AP*AP*AP*AP*A)-3'), Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: single-stranded rna, methyltransferase, rna cap, poly(a) polymerase, vaccinia, mrna processing, transcription, complex (transferase-rna), transferase-rna complex, transferase/rna
• Biological source: Vaccinia virus WR (VACV)
• Total number of polymer chains: 2
• Total formula weight: 37442.92

Authors

Hodel, A.E.,Gershon, P.D.,Quiocho, F.A. (deposition date: 1997-09-26, release date: 1998-02-25, Last modification date: 2023-08-02)

• Primary citation: Hodel, A.E.,Gershon, P.D.,Quiocho, F.A.; Structural basis for sequence-nonspecific recognition of 5'-capped mRNA by a cap-modifying enzyme.; Mol.Cell, 1:443-447, 1998; PubMed: 9660928; DOI: 10.1016/S1097-2765(00)80044-1

Experimental method

X-RAY DIFFRACTION (2.8 Å)