1AUK
HUMAN ARYLSULFATASE A
Summary for 1AUK
Entry DOI | 10.2210/pdb1auk/pdb |
Descriptor | ARYLSULFATASE A, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | cerebroside-3-sulfate hydrolysis, lysosomal enzyme, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Lysosome: P15289 |
Total number of polymer chains | 1 |
Total formula weight | 52405.44 |
Authors | Lukatela, G.,Krauss, N.,Theis, K.,Gieselmann, V.,Von Figura, K.,Saenger, W. (deposition date: 1997-08-29, release date: 1998-03-04, Last modification date: 2020-07-29) |
Primary citation | Lukatela, G.,Krauss, N.,Theis, K.,Selmer, T.,Gieselmann, V.,von Figura, K.,Saenger, W. Crystal structure of human arylsulfatase A: the aldehyde function and the metal ion at the active site suggest a novel mechanism for sulfate ester hydrolysis. Biochemistry, 37:3654-3664, 1998 Cited by PubMed: 9521684DOI: 10.1021/bi9714924 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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