1AQU

ESTROGEN SULFOTRANSFERASE WITH BOUND INACTIVE COFACTOR PAP AND 17-BETA ESTRADIOL

1AQU の概要

• エントリーDOI: 10.2210/pdb1aqu/pdb
• 分子名称: ESTROGEN SULFOTRANSFERASE, ADENOSINE-3'-5'-DIPHOSPHATE, ESTRADIOL, ... (4 entities in total)
• 機能のキーワード: transferase, pap, sulfotransferase, sulfonation, estrogen, 17-beta estradiol, steroid-binding
• 由来する生物種: Mus musculus (house mouse)
• 細胞内の位置: Cytoplasm: P49891
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 72967.85

構造登録者

Kakuta, Y.,Negishi, M.,Pedersen, L.C. (登録日: 1997-08-01, 公開日: 1998-10-28, 最終更新日: 2024-05-22)

主引用文献

Kakuta, Y.,Pedersen, L.G.,Carter, C.W.,Negishi, M.,Pedersen, L.C.
Crystal structure of estrogen sulphotransferase.
Nat.Struct.Biol., 4:904-908, 1997

PubMed Abstract: The structure of estrogen sulphotransferase has been solved in the presence of inactive cofactor PAP and substrate 17 beta-estradiol. This structure reveals structural similarities between cytosolic sulphotransferases and nucleotide kinases.

PubMed: 9360604
DOI: 10.1038/nsb1197-904

実験手法

X-RAY DIFFRACTION (1.6 Å)