1APW

CRYSTALLOGRAPHIC ANALYSIS OF TRANSITION STATE MIMICS BOUND TO PENICILLOPEPSIN: DIFLUOROSTATINE-AND DIFLUOROSTATONE-CONTAINING PEPTIDES

1APW の概要

• エントリーDOI: 10.2210/pdb1apw/pdb
• 関連するPDBエントリー: 1APT 1APU 1APV
• 分子名称: PENICILLOPEPSIN, INHIBITOR ISOVALERYL (IVA)-VAL-VAL-DIFLUOROSTATINE-N-METHYLAMINE, alpha-D-mannopyranose, ... (7 entities in total)
• 機能のキーワード: acid proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Penicillium janthinellum (Penicillium vitale)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 34474.88

構造登録者

Sielecki, A.R.,James, M.N.G. (登録日: 1991-12-16, 公開日: 1994-01-31, 最終更新日: 2020-07-29)

• 主引用文献: James, M.N.,Sielecki, A.R.,Hayakawa, K.,Gelb, M.H.; Crystallographic analysis of transition state mimics bound to penicillopepsin: difluorostatine- and difluorostatone-containing peptides.; Biochemistry, 31:3872-3886, 1992; PubMed: 1567842; DOI: 10.1021/bi00130a019

実験手法

X-RAY DIFFRACTION (1.8 Å)