1AOU
NMR STRUCTURE OF THE FYN SH2 DOMAIN COMPLEXED WITH A PHOSPHOTYROSYL PEPTIDE, 22 STRUCTURES
Summary for 1AOU
Entry DOI | 10.2210/pdb1aou/pdb |
Related | 1AOT |
Descriptor | FYN PROTEIN-TYROSINE KINASE, PHOSPHOTYROSYL PEPTIDE (2 entities in total) |
Functional Keywords | sh2 domain, signal transduction, peptide complex, complex (proto-oncogene-early protein), complex (proto-oncogene-early protein) complex, complex (proto-oncogene/early protein) |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane: P06241 Host membrane; Single-pass membrane protein (Potential): P03079 |
Total number of polymer chains | 2 |
Total formula weight | 13773.33 |
Authors | Mulhern, T.D.,Shaw, G.L.,Morton, C.J.,Day, A.J.,Campbell, I.D. (deposition date: 1997-07-10, release date: 1998-01-14, Last modification date: 2021-11-03) |
Primary citation | Mulhern, T.D.,Shaw, G.L.,Morton, C.J.,Day, A.J.,Campbell, I.D. The SH2 domain from the tyrosine kinase Fyn in complex with a phosphotyrosyl peptide reveals insights into domain stability and binding specificity. Structure, 5:1313-1323, 1997 Cited by PubMed: 9351806DOI: 10.1016/S0969-2126(97)00283-9 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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