1AMP

CRYSTAL STRUCTURE OF AEROMONAS PROTEOLYTICA AMINOPEPTIDASE: A PROTOTYPICAL MEMBER OF THE CO-CATALYTIC ZINC ENZYME FAMILY

1AMP の概要

• エントリーDOI: 10.2210/pdb1amp/pdb
• 分子名称: AMINOPEPTIDASE, ZINC ION (3 entities in total)
• 機能のキーワード: hydrolase(aminopeptidase)
• 由来する生物種: Vibrio proteolyticus
• 細胞内の位置: Secreted: Q01693
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 31558.17

構造登録者

Chevrier, B.,Schalk, C.,D'Orchymont, H.,Rondeau, J.M.,Moras, D.,Tarnus, C. (登録日: 1994-04-22, 公開日: 1994-08-31, 最終更新日: 2024-10-30)

主引用文献

Chevrier, B.,Schalk, C.,D'Orchymont, H.,Rondeau, J.M.,Moras, D.,Tarnus, C.
Crystal structure of Aeromonas proteolytica aminopeptidase: a prototypical member of the co-catalytic zinc enzyme family.
Structure, 2:283-291, 1994

PubMed Abstract: Aminopeptidases specifically cleave the amino-terminal residue from polypeptide chains and are involved in the metabolism of biologically active peptides. The family includes zinc-dependent enzymes possessing either one or two zinc ions per active site. Structural studies providing a detailed view of the metal environment may reveal whether the one-zinc and two-zinc enzymes constitute structurally and mechanistically distinct subclasses, and what role the metal ions play in the catalytic process.

PubMed: 8087555
DOI: 10.1016/S0969-2126(00)00030-7

実験手法

X-RAY DIFFRACTION (1.8 Å)