1AKJ

COMPLEX OF THE HUMAN MHC CLASS I GLYCOPROTEIN HLA-A2 AND THE T CELL CORECEPTOR CD8

1AKJ の概要

• エントリーDOI: 10.2210/pdb1akj/pdb
• 分子名称: MHC CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A*0201) (ALPHA CHAIN), BETA 2-MICROGLOBULIN, HIV REVERSE TRANSCRIPTASE EPITOPE, ... (5 entities in total)
• 機能のキーワード: t-cell, glycoprotein, complex, immunology, complex (mhc i-peptide-cd8), complex (mhc i-peptide-cd8) complex, complex (mhc i/peptide/cd8)
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P01892; Secreted: P61769; Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted: P01732
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 71645.22

構造登録者

Tormo, J.,Stuart, D.I.,Jones, E.Y. (登録日: 1997-05-21, 公開日: 1997-09-17, 最終更新日: 2023-08-02)

• 主引用文献: Gao, G.F.,Tormo, J.,Gerth, U.C.,Wyer, J.R.,McMichael, A.J.,Stuart, D.I.,Bell, J.I.,Jones, E.Y.,Jakobsen, B.K.; Crystal structure of the complex between human CD8alpha(alpha) and HLA-A2.; Nature, 387:630-634, 1997; PubMed: 9177355; DOI: 10.1038/42523

実験手法

X-RAY DIFFRACTION (2.65 Å)