1AI1
HIV-1 V3 LOOP MIMIC
Summary for 1AI1
Entry DOI | 10.2210/pdb1ai1/pdb |
Descriptor | IGG1-KAPPA 59.1 FAB (LIGHT CHAIN), IGG1-KAPPA 59.1 FAB (HEAVY CHAIN), AIB142 (3 entities in total) |
Functional Keywords | complex (antibody-peptide), antibody, constrained hiv-1 v3 loop peptide, immunoglobulin, complex (antibody-peptide) complex, complex (antibody/peptide) |
Biological source | Mus musculus (house mouse) More |
Cellular location | Isoform Secreted: Secreted: P01868 Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: P05877 |
Total number of polymer chains | 3 |
Total formula weight | 50711.86 |
Authors | Ghiara, J.B.,Wilson, I.A. (deposition date: 1996-11-06, release date: 1997-05-15, Last modification date: 2023-08-02) |
Primary citation | Ghiara, J.B.,Ferguson, D.C.,Satterthwait, A.C.,Dyson, H.J.,Wilson, I.A. Structure-based design of a constrained peptide mimic of the HIV-1 V3 loop neutralization site. J.Mol.Biol., 266:31-39, 1997 Cited by PubMed: 9054968DOI: 10.1006/jmbi.1996.0768 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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