1AHA

THE N-GLYCOSIDASE MECHANISM OF RIBOSOME-INACTIVATING PROTEINS IMPLIED BY CRYSTAL STRUCTURES OF ALPHA-MOMORCHARIN

Summary for 1AHA

Entry DOI	10.2210/pdb1aha/pdb
Descriptor	ALPHA-MOMORCHARIN, ADENINE (3 entities in total)
Functional Keywords	glycosidase
Biological source	Momordica charantia (balsam pear)
Total number of polymer chains	1
Total formula weight	27531.41
Authors	Ren, J.,Wang, Y.,Dong, Y.,Stuart, D.I. (deposition date: 1994-01-07, release date: 1994-06-22, Last modification date: 2024-02-07)
Primary citation	Ren, J.,Wang, Y.,Dong, Y.,Stuart, D.I. The N-glycosidase mechanism of ribosome-inactivating proteins implied by crystal structures of alpha-momorcharin. Structure, 2:7-16, 1994 Cited by PubMed Abstract: alpha-Momorcharin (alpha MMC) is a type I ribosome-inactivating protein. It inhibits protein synthesis by hydrolytically removing a specific adenine residue from a highly conserved, single-stranded loop of rRNA. PubMed: 8075985 DOI: 10.1016/S0969-2126(00)00004-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation