1AHA

THE N-GLYCOSIDASE MECHANISM OF RIBOSOME-INACTIVATING PROTEINS IMPLIED BY CRYSTAL STRUCTURES OF ALPHA-MOMORCHARIN

1AHA の概要

• エントリーDOI: 10.2210/pdb1aha/pdb
• 分子名称: ALPHA-MOMORCHARIN, ADENINE (3 entities in total)
• 機能のキーワード: glycosidase
• 由来する生物種: Momordica charantia (balsam pear)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 27531.41

構造登録者

Ren, J.,Wang, Y.,Dong, Y.,Stuart, D.I. (登録日: 1994-01-07, 公開日: 1994-06-22, 最終更新日: 2024-02-07)

主引用文献

Ren, J.,Wang, Y.,Dong, Y.,Stuart, D.I.
The N-glycosidase mechanism of ribosome-inactivating proteins implied by crystal structures of alpha-momorcharin.
Structure, 2:7-16, 1994

PubMed Abstract: alpha-Momorcharin (alpha MMC) is a type I ribosome-inactivating protein. It inhibits protein synthesis by hydrolytically removing a specific adenine residue from a highly conserved, single-stranded loop of rRNA.

PubMed: 8075985
DOI: 10.1016/S0969-2126(00)00004-6

実験手法

X-RAY DIFFRACTION (2.2 Å)