1AH1

CTLA-4, NMR, 20 STRUCTURES

Summary for 1AH1

Entry DOI	10.2210/pdb1ah1/pdb
Descriptor	CTLA-4, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	immunoreceptor, t cell receptor, immune response, immunoglobulin
Biological source	Homo sapiens (human)
Cellular location	Cell membrane; Single-pass type I membrane protein: P16410
Total number of polymer chains	1
Total formula weight	15330.06
Authors	Metzler, W.J.,Bajorath, J.,Fenderson, W.,Shaw, S.-Y.,Peach, R.,Constantine, K.L.,Naemura, J.,Leytze, G.,Lavoie, T.B.,Mueller, L.,Linsley, P.S. (deposition date: 1997-04-11, release date: 1998-04-15, Last modification date: 2020-07-29)
Primary citation	Metzler, W.J.,Bajorath, J.,Fenderson, W.,Shaw, S.Y.,Constantine, K.L.,Naemura, J.,Leytze, G.,Peach, R.J.,Lavoie, T.B.,Mueller, L.,Linsley, P.S. Solution structure of human CTLA-4 and delineation of a CD80/CD86 binding site conserved in CD28. Nat.Struct.Biol., 4:527-531, 1997 Cited by PubMed: 9228944 DOI: 10.1038/nsb0797-527 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation