1AGR

COMPLEX OF ALF4-ACTIVATED GI-ALPHA-1 WITH RGS4

Summary for 1AGR

Entry DOI	10.2210/pdb1agr/pdb
Descriptor	GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), RGS4, MAGNESIUM ION, ... (7 entities in total)
Functional Keywords	gi-alpha-1, hydrolase, signal transduction, rgs4, complex (signal transduction-regulator), gtp-binding, gtpase activating protein, complex (signal transduction-regulator) complex, complex (signal transduction/regulator)
Biological source	Rattus norvegicus (Norway rat) More
Cellular location	Nucleus: P10824
Total number of polymer chains	4
Total formula weight	128634.28
Authors	Tesmer, J.J.G.,Sprang, S.R. (deposition date: 1997-03-25, release date: 1997-06-16, Last modification date: 2023-08-02)
Primary citation	Tesmer, J.J.,Berman, D.M.,Gilman, A.G.,Sprang, S.R. Structure of RGS4 bound to AlF4--activated G(i alpha1): stabilization of the transition state for GTP hydrolysis. Cell(Cambridge,Mass.), 89:251-261, 1997 Cited by PubMed: 9108480 DOI: 10.1016/S0092-8674(00)80204-4 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation