1AFS

RECOMBINANT RAT LIVER 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE (3-ALPHA-HSD) COMPLEXED WITH NADP AND TESTOSTERONE

1AFS の概要

• エントリーDOI: 10.2210/pdb1afs/pdb
• 分子名称: 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TESTOSTERONE, ... (4 entities in total)
• 機能のキーワード: oxidoreductase, nad
• 由来する生物種: Rattus norvegicus (Norway rat)
• 細胞内の位置: Cytoplasm: P23457
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 76448.95

構造登録者

Bennett, M.J.,Albert, R.H.,Jez, J.M.,Ma, H.,Penning, T.M.,Lewis, M. (登録日: 1997-03-13, 公開日: 1997-10-08, 最終更新日: 2024-05-22)

• 主引用文献: Bennett, M.J.,Albert, R.H.,Jez, J.M.,Ma, H.,Penning, T.M.,Lewis, M.; Steroid recognition and regulation of hormone action: crystal structure of testosterone and NADP+ bound to 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase.; Structure, 5:799-812, 1997; PubMed: 9261071; DOI: 10.1016/S0969-2126(97)00234-7

実験手法

X-RAY DIFFRACTION (2.5 Å)