1AEM

SPECIFICITY OF LIGAND BINDING TO A BURIED POLAR CAVITY AT THE ACTIVE SITE OF CYTOCHROME C PEROXIDASE (IMIDAZO[1,2-A]PYRIDINE)

1AEM の概要

• エントリーDOI: 10.2210/pdb1aem/pdb
• 分子名称: CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, IMIDAZO[1,2-A]PYRIDINE, ... (4 entities in total)
• 機能のキーワード: oxidoreductase, peroxidase, transit peptide
• 由来する生物種: Saccharomyces cerevisiae (baker's yeast)
• 細胞内の位置: Mitochondrion matrix: P00431
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34194.87

構造登録者

Musah, R.A.,Jensen, G.M.,Fitzgerald, M.M.,Mcree, D.E.,Goodin, D.B. (登録日: 1997-02-25, 公開日: 1997-09-04, 最終更新日: 2024-05-22)

• 主引用文献: Musah, R.A.,Jensen, G.M.,Bunte, S.W.,Rosenfeld, R.J.,Goodin, D.B.; Artificial protein cavities as specific ligand-binding templates: characterization of an engineered heterocyclic cation-binding site that preserves the evolved specificity of the parent protein.; J.Mol.Biol., 315:845-857, 2002; PubMed: 11812152; DOI: 10.1006/jmbi.2001.5287

実験手法

X-RAY DIFFRACTION (2.1 Å)