1AE6
IGG-FAB FRAGMENT OF MOUSE MONOCLONAL ANTIBODY CTM01
Summary for 1AE6
Entry DOI | 10.2210/pdb1ae6/pdb |
Descriptor | IGG CTM01 FAB (LIGHT CHAIN), IGG CTM01 FAB (HEAVY CHAIN) (2 entities in total) |
Functional Keywords | immunoglobulin, fab fragment, humanisation |
Biological source | Mus musculus (house mouse) More |
Cellular location | Cell membrane; Single-pass membrane protein (Potential): P01869 |
Total number of polymer chains | 2 |
Total formula weight | 47664.26 |
Authors | Banfield, M.J.,Brady, R.L. (deposition date: 1997-03-06, release date: 1998-03-18, Last modification date: 2023-08-02) |
Primary citation | Banfield, M.J.,King, D.J.,Mountain, A.,Brady, R.L. VL:VH domain rotations in engineered antibodies: crystal structures of the Fab fragments from two murine antitumor antibodies and their engineered human constructs. Proteins, 29:161-171, 1997 Cited by PubMed: 9329081DOI: 10.1002/(SICI)1097-0134(199710)29:2<161::AID-PROT4>3.0.CO;2-G PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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