1ADG

CRYSTALLOGRAPHIC STUDIES OF TWO ALCOHOL DEHYDROGENASE-BOUND ANALOGS OF THIAZOLE-4-CARBOXAMIDE ADENINE DINUCLEOTIDE (TAD), THE ACTIVE ANABOLITE OF THE ANTITUMOR AGENT TIAZOFURIN

1ADG の概要

• エントリーDOI: 10.2210/pdb1adg/pdb
• 分子名称: ALCOHOL DEHYDROGENASE, ZINC ION, BETA-METHYLENE-SELENAZOLE-4-CARBOXYAMIDE-ADENINE DINUCLEOTIDE, ... (4 entities in total)
• 機能のキーワード: oxidoreductase(nad(a)-choh(d))
• 由来する生物種: Equus caballus (horse)
• 細胞内の位置: Cytoplasm: P00327
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 40698.47

構造登録者

Li, H.,Hallows, W.A.,Punzi, J.S.,Marquez, V.E.,Carrell, H.L.,Pankiewicz, K.W.,Watanabe, K.A.,Goldstein, B.M. (登録日: 1993-10-18, 公開日: 1994-01-31, 最終更新日: 2024-02-07)

• 主引用文献: Li, H.,Hallows, W.H.,Punzi, J.S.,Marquez, V.E.,Carrell, H.L.,Pankiewicz, K.W.,Watanabe, K.A.,Goldstein, B.M.; Crystallographic studies of two alcohol dehydrogenase-bound analogues of thiazole-4-carboxamide adenine dinucleotide (TAD), the active anabolite of the antitumor agent tiazofurin.; Biochemistry, 33:23-32, 1994; PubMed: 8286346; DOI: 10.1021/bi00167a004

実験手法

X-RAY DIFFRACTION (2.7 Å)