1AD0
FAB FRAGMENT OF ENGINEERED HUMAN MONOCLONAL ANTIBODY A5B7
Summary for 1AD0
Entry DOI | 10.2210/pdb1ad0/pdb |
Descriptor | ANTIBODY A5B7 (LIGHT CHAIN), ANTIBODY A5B7 (HEAVY CHAIN) (3 entities in total) |
Functional Keywords | immunoglobulin, fab fragment |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 94026.71 |
Authors | Banfield, M.J.,Brady, R.L. (deposition date: 1997-02-19, release date: 1998-02-25, Last modification date: 2023-08-02) |
Primary citation | Banfield, M.J.,King, D.J.,Mountain, A.,Brady, R.L. VL:VH domain rotations in engineered antibodies: crystal structures of the Fab fragments from two murine antitumor antibodies and their engineered human constructs. Proteins, 29:161-171, 1997 Cited by PubMed: 9329081DOI: 10.1002/(SICI)1097-0134(199710)29:2<161::AID-PROT4>3.0.CO;2-G PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report