1ACL
QUATERNARY LIGAND BINDING TO AROMATIC RESIDUES IN THE ACTIVE-SITE GORGE OF ACETYLCHOLINESTERASE
Summary for 1ACL
Entry DOI | 10.2210/pdb1acl/pdb |
Descriptor | ACETYLCHOLINESTERASE, DECAMETHONIUM ION (3 entities in total) |
Functional Keywords | hydrolase(carboxylic esterase) |
Biological source | Torpedo californica (Pacific electric ray) |
Cellular location | Isoform H: Cell membrane; Lipid-anchor, GPI- anchor. Isoform T: Cell membrane; Peripheral membrane protein: P04058 |
Total number of polymer chains | 1 |
Total formula weight | 61051.00 |
Authors | Sussman, J.L.,Harel, M.,Silman, I. (deposition date: 1993-08-18, release date: 1994-08-31, Last modification date: 2024-01-17) |
Primary citation | Harel, M.,Schalk, I.,Ehret-Sabatier, L.,Bouet, F.,Goeldner, M.,Hirth, C.,Axelsen, P.H.,Silman, I.,Sussman, J.L. Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase. Proc.Natl.Acad.Sci.USA, 90:9031-9035, 1993 Cited by PubMed: 8415649DOI: 10.1073/pnas.90.19.9031 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)