1A9U

THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB203580

Summary for 1A9U

Entry DOI	10.2210/pdb1a9u/pdb
Descriptor	MAP KINASE P38, 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE (3 entities in total)
Functional Keywords	transferase, map kinase, serine/threonine-protein kinase, p38
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm : Q16539
Total number of polymer chains	1
Total formula weight	43760.79
Authors	Wang, Z.,Canagarajah, B.,Boehm, J.C.,Kassis, S.,Cobb, M.H.,Young, P.R.,Abdel-Meguid, S.,Adams, J.L.,Goldsmith, E.J. (deposition date: 1998-04-10, release date: 1999-04-20, Last modification date: 2024-04-03)
Primary citation	Wang, Z.,Canagarajah, B.J.,Boehm, J.C.,Kassisa, S.,Cobb, M.H.,Young, P.R.,Abdel-Meguid, S.,Adams, J.L.,Goldsmith, E.J. Structural basis of inhibitor selectivity in MAP kinases. Structure, 6:1117-1128, 1998 Cited by PubMed: 9753691 DOI: 10.1016/S0969-2126(98)00113-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation