1A7C

HUMAN PLASMINOGEN ACTIVATOR INHIBITOR TYPE-1 IN COMPLEX WITH A PENTAPEPTIDE

1A7C の概要

• エントリーDOI: 10.2210/pdb1a7c/pdb
• 分子名称: PLASMINOGEN ACTIVATOR INHIBITOR TYPE 1, PENTAPEPTIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-D-ribopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: serine protease inhibitor, pai-1, carbohydrate, inhibitor complex, protease inhibitor-peptide complex, hydrolase inhibitor-peptide complex, hydrolase inhibitor/peptide
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 44629.88

構造登録者

Xue, Y.,Inghardt, T.,Sjolin, L.,Deinum, J. (登録日: 1998-03-12, 公開日: 1999-03-23, 最終更新日: 2020-07-29)

• 主引用文献: Xue, Y.,Bjorquist, P.,Inghardt, T.,Linschoten, M.,Musil, D.,Sjolin, L.,Deinum, J.; Interfering with the inhibitory mechanism of serpins: crystal structure of a complex formed between cleaved plasminogen activator inhibitor type 1 and a reactive-centre loop peptide; Structure, 6:627-636, 1998; PubMed: 9634700; DOI: 10.1016/S0969-2126(98)00064-1

実験手法

X-RAY DIFFRACTION (1.95 Å)