1A71

TERNARY COMPLEX OF AN ACTIVE SITE DOUBLE MUTANT OF HORSE LIVER ALCOHOL DEHYDROGENASE, PHE93=>TRP, VAL203=>ALA WITH NAD AND TRIFLUOROETHANOL

Summary for 1A71

Entry DOI	10.2210/pdb1a71/pdb
Descriptor	LIVER ALCOHOL DEHYDROGENASE, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (5 entities in total)
Functional Keywords	oxidoreductase (nad(a)-choh(d)), liver, alcohol, dehydrogenase, ladh, active site mutant, oxidoreductase
Biological source	Equus caballus (horse)
Cellular location	Cytoplasm: P00327
Total number of polymer chains	2
Total formula weight	81517.08
Authors	Colby, T.D.,Bahnson, B.J.,Chin, J.K.,Klinman, J.P.,Goldstein, B.M. (deposition date: 1998-03-19, release date: 1998-06-17, Last modification date: 2023-08-02)
Primary citation	Colby, T.D.,Bahnson, B.J.,Chin, J.K.,Klinman, J.P.,Goldstein, B.M. Active site modifications in a double mutant of liver alcohol dehydrogenase: structural studies of two enzyme-ligand complexes. Biochemistry, 37:9295-9304, 1998 Cited by PubMed: 9649310 DOI: 10.1021/bi973184b PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation