1A5G
HUMAN THROMBIN COMPLEXED WITH NOVEL SYNTHETIC PEPTIDE MIMETIC INHIBITOR AND HIRUGEN
Summary for 1A5G
| Entry DOI | 10.2210/pdb1a5g/pdb |
| Related PRD ID | PRD_000618 |
| Descriptor | ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), HIRUGEN, ... (6 entities in total) |
| Functional Keywords | complex (serine protease-inhibitor), hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Homo sapiens (human) More |
| Cellular location | Secreted, extracellular space: P00734 P09945 Secreted: P00734 |
| Total number of polymer chains | 3 |
| Total formula weight | 36035.99 |
| Authors | St Charles, R.,Tulinsky, A.,Kahn, M. (deposition date: 1998-02-16, release date: 1998-05-27, Last modification date: 2012-12-12) |
| Primary citation | St Charles, R.,Matthews, J.H.,Zhang, E.,Tulinsky, A. Bound structures of novel P3-P1' beta-strand mimetic inhibitors of thrombin. J.Med.Chem., 42:1376-1383, 1999 Cited by PubMed: 10212123DOI: 10.1021/jm980052n PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.06 Å) |
Structure validation
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