1A5G

HUMAN THROMBIN COMPLEXED WITH NOVEL SYNTHETIC PEPTIDE MIMETIC INHIBITOR AND HIRUGEN

1A5G の概要

• エントリーDOI: 10.2210/pdb1a5g/pdb
• 関連するBIRD辞書のPRD_ID: PRD_000618
• 分子名称: ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), HIRUGEN, ... (6 entities in total)
• 機能のキーワード: complex (serine protease-inhibitor), hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted, extracellular space: P00734 P09945; Secreted: P00734
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 36035.99

構造登録者

St Charles, R.,Tulinsky, A.,Kahn, M. (登録日: 1998-02-16, 公開日: 1998-05-27, 最終更新日: 2012-12-12)

• 主引用文献: St Charles, R.,Matthews, J.H.,Zhang, E.,Tulinsky, A.; Bound structures of novel P3-P1' beta-strand mimetic inhibitors of thrombin.; J.Med.Chem., 42:1376-1383, 1999; PubMed: 10212123; DOI: 10.1021/jm980052n

実験手法

X-RAY DIFFRACTION (2.06 Å)