1A4G

INFLUENZA VIRUS B/BEIJING/1/87 NEURAMINIDASE COMPLEXED WITH ZANAMIVIR

1A4G の概要

• エントリーDOI: 10.2210/pdb1a4g/pdb
• 分子名称: NEURAMINIDASE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (5 entities in total)
• 機能のキーワード: hydrolase, glycosidase, glycosylated protein
• 由来する生物種: Influenza B virus (STRAIN B/BEIJING/1/87)
• 細胞内の位置: Virion membrane : P27907
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 88085.78

構造登録者

Cleasby, A.,Singh, O.,Skarzynski, T.,Wonacott, A.J. (登録日: 1998-01-29, 公開日: 1999-03-02, 最終更新日: 2023-08-02)

• 主引用文献: Taylor, N.R.,Cleasby, A.,Singh, O.,Skarzynski, T.,Wonacott, A.J.,Smith, P.W.,Sollis, S.L.,Howes, P.D.,Cherry, P.C.,Bethell, R.,Colman, P.,Varghese, J.; Dihydropyrancarboxamides related to zanamivir: a new series of inhibitors of influenza virus sialidases. 2. Crystallographic and molecular modeling study of complexes of 4-amino-4H-pyran-6-carboxamides and sialidase from influenza virus types A and B.; J.Med.Chem., 41:798-807, 1998; PubMed: 9526556; DOI: 10.1021/jm9703754

実験手法

X-RAY DIFFRACTION (2.2 Å)