1A36

TOPOISOMERASE I/DNA COMPLEX

Summary for 1A36

• Entry DOI: 10.2210/pdb1a36/pdb
• Descriptor: DNA (5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*TP*AP*GP*AP*AP*AP*AP*A P*TP*TP*TP*TP*T)- 3'), DNA (5'-D(*AP*AP*AP*AP*AP*TP*TP*TP*TP*TP*CP*TP*AP*AP*GP*TP*C P*TP*TP*TP*TP*T)- 3'), TOPOISOMERASE I, ... (4 entities in total)
• Functional Keywords: complex (isomerase-dna), dna, topoisomerase i, isomerase-dna complex, isomerase/dna
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus, nucleolus: P11387
• Total number of polymer chains: 3
• Total formula weight: 83518.70

Authors

Stewart, L.,Redinbo, M.R.,Qiu, X.,Champoux, J.J.,Hol, W.G.J. (deposition date: 1998-01-29, release date: 1998-08-12, Last modification date: 2024-04-03)

• Primary citation: Stewart, L.,Redinbo, M.R.,Qiu, X.,Hol, W.G.,Champoux, J.J.; A model for the mechanism of human topoisomerase I.; Science, 279:1534-1541, 1998; PubMed: 9488652; DOI: 10.1126/science.279.5356.1534

Experimental method

X-RAY DIFFRACTION (2.8 Å)