1A36

TOPOISOMERASE I/DNA COMPLEX

Summary for 1A36

DescriptorDNA (5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*TP*AP*GP*AP*AP*AP*AP*A P*TP*TP*TP*TP*T)- 3'), DNA (5'-D(*AP*AP*AP*AP*AP*TP*TP*TP*TP*TP*CP*TP*AP*AP*GP*TP*C P*TP*TP*TP*TP*T)- 3'), TOPOISOMERASE I, ... (4 entities in total)
Functional Keywordscomplex (isomerase-dna), dna, topoisomerase i, isomerase-dna complex, isomerase/dna
Biological sourceHomo sapiens (human)
Cellular locationNucleus, nucleolus P11387
Total number of polymer chains3
Total molecular weight83518.7
Authors
Stewart, L.,Redinbo, M.R.,Qiu, X.,Champoux, J.J.,Hol, W.G.J. (deposition date: 1998-01-29, release date: 1998-08-12, Last modification date: 2011-07-13)
Primary citation
Stewart, L.,Redinbo, M.R.,Qiu, X.,Hol, W.G.,Champoux, J.J.
A model for the mechanism of human topoisomerase I.
Science, 279:1534-1541, 1998
PubMed: 9488652 (PDB entries with the same primary citation)
DOI: 10.1126/science.279.5356.1534
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.8 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers260.6%4.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution