1A2N
STRUCTURE OF THE C115A MUTANT OF MURA COMPLEXED WITH THE FLUORINATED ANALOG OF THE REACTION TETRAHEDRAL INTERMEDIATE
Summary for 1A2N
Entry DOI | 10.2210/pdb1a2n/pdb |
Descriptor | UDP-N-ACETYLGLUCOSAMINE ENOLPYRUVYL TRANSFERASE, URIDINE-DIPHOSPHATE-2(N-ACETYLGLUCOSAMINYL-3-FLUORO-2-PHOSPHONOOXY)PROPIONIC ACID (3 entities in total) |
Functional Keywords | transferase, peptidoglycan synthesis, enolpyruvyl transferase, udp-n-acetylglucosamine |
Biological source | Escherichia coli |
Total number of polymer chains | 1 |
Total formula weight | 45632.86 |
Authors | Skarzynski, T. (deposition date: 1998-01-06, release date: 1998-04-29, Last modification date: 2024-05-22) |
Primary citation | Skarzynski, T.,Kim, D.H.,Lees, W.J.,Walsh, C.T.,Duncan, K. Stereochemical course of enzymatic enolpyruvyl transfer and catalytic conformation of the active site revealed by the crystal structure of the fluorinated analogue of the reaction tetrahedral intermediate bound to the active site of the C115A mutant of MurA Biochemistry, 37:2572-2577, 1998 Cited by PubMed: 9485407DOI: 10.1021/bi9722608 PDB entries with the same primary citation |
Experimental method |
Structure validation
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