1A22
HUMAN GROWTH HORMONE BOUND TO SINGLE RECEPTOR
Summary for 1A22
Entry DOI | 10.2210/pdb1a22/pdb |
Descriptor | GROWTH HORMONE, GROWTH HORMONE RECEPTOR (3 entities in total) |
Functional Keywords | complex (hormone-receptor), pituitary, hormone, complex (hormone-receptor) complex, complex (hormone/receptor) |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P01241 Cell membrane; Single-pass type I membrane protein. Isoform 2: Cell membrane; Single-pass type I membrane protein. Growth hormone-binding protein: Secreted: P10912 |
Total number of polymer chains | 2 |
Total formula weight | 49661.91 |
Authors | De Vos, A.M.,Ultsch, M. (deposition date: 1998-01-15, release date: 1998-04-29, Last modification date: 2023-08-02) |
Primary citation | Clackson, T.,Ultsch, M.H.,Wells, J.A.,de Vos, A.M. Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity. J.Mol.Biol., 277:1111-1128, 1998 Cited by PubMed: 9571026DOI: 10.1006/jmbi.1998.1669 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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