1A0S

SUCROSE-SPECIFIC PORIN

1A0S の概要

• エントリーDOI: 10.2210/pdb1a0s/pdb
• 分子名称: SUCROSE-SPECIFIC PORIN, CALCIUM ION (3 entities in total)
• 機能のキーワード: outer membrane protein, porin
• 由来する生物種: Salmonella typhimurium
• 細胞内の位置: Cell outer membrane; Multi-pass membrane protein: P22340
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 136121.24

構造登録者

Diederichs, K.,Welte, W. (登録日: 1997-12-07, 公開日: 1998-06-10, 最終更新日: 2024-02-07)

主引用文献

Forst, D.,Welte, W.,Wacker, T.,Diederichs, K.
Structure of the sucrose-specific porin ScrY from Salmonella typhimurium and its complex with sucrose.
Nat.Struct.Biol., 5:37-46, 1998

PubMed Abstract: The X-ray structure of a sucrose-specific porin (ScrY) from Salmonella typhimurium has been determined by multiple isomorphous replacement at 2.4 A resolution both in its uncomplexed form and with bound sucrose. ScrY is a noncrystallographic trimer of identical subunits, each with 413 structurally well-defined amino acids. A monomer is built up of 18 anti-parallel beta-strands surrounding a hydrophilic pore, with a topology closely similar to that of maltoporin. Two non-overlapping sucrose-binding sites were identified in difference Fourier maps. The higher permeability for sucrose of ScrY as compared to maltoporin is mainly accounted for by differences in their pore-lining residues.

PubMed: 9437428
DOI: 10.1038/nsb0198-37

実験手法

X-RAY DIFFRACTION (2.4 Å)