1A0B
HISTIDINE-CONTAINING PHOSPHOTRANSFER DOMAIN OF ARCB FROM ESCHERICHIA COLI
Summary for 1A0B
| Entry DOI | 10.2210/pdb1a0b/pdb |
| Descriptor | AEROBIC RESPIRATION CONTROL SENSOR PROTEIN ARCB, ZINC ION (3 entities in total) |
| Functional Keywords | histidine kinase, phosphotransfer, two-component system, four-helix bundle |
| Biological source | Escherichia coli |
| Total number of polymer chains | 1 |
| Total formula weight | 14079.35 |
| Authors | Kato, M.,Mizuno, T.,Shimizu, T.,Hakoshima, T. (deposition date: 1997-11-27, release date: 1998-03-18, Last modification date: 2024-02-07) |
| Primary citation | Kato, M.,Mizuno, T.,Shimizu, T.,Hakoshima, T. Insights into multistep phosphorelay from the crystal structure of the C-terminal HPt domain of ArcB. Cell(Cambridge,Mass.), 88:717-723, 1997 Cited by PubMed Abstract: The histidine-containing phosphotransfer (HPt) domain is a novel protein module with an active histidine residue that mediates phosphotransfer reactions in the two-component signaling systems. A multistep phosphorelay involving the HPt domain has been suggested for these signaling pathways. The crystal structure of the HPt domain of the anaerobic sensor kinase ArcB has been determined at 2.06 A resolution. The domain consists of six alpha helices containing a four-helix bundle-folding. The pattern of sequence similarity of the HPt domains of ArcB and components in other signaling systems can be interpreted in light of the three-dimensional structure and supports the conclusion that the HPt domains have a common structural motif both in prokaryotes and eukaryotes. PubMed: 9054511DOI: 10.1016/S0092-8674(00)81914-5 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.06 Å) |
Structure validation
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