1ZP5
Crystal structure of the complex between MMP-8 and a N-hydroxyurea inhibitor
Summary for 1ZP5
Entry DOI | 10.2210/pdb1zp5/pdb |
Descriptor | Neutrophil collagenase, CALCIUM ION, ZINC ION, ... (5 entities in total) |
Functional Keywords | hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasmic granule: P22894 |
Total number of polymer chains | 1 |
Total formula weight | 18634.05 |
Authors | Campestre, C.,Agamennone, M.,Tortorella, P.,Preziuso, S.,Biasone, A.,Gavuzzo, E.,Pochetti, G.,Mazza, F.,Tschesche, H.,Gallina, C. (deposition date: 2005-05-16, release date: 2005-12-06, Last modification date: 2023-08-23) |
Primary citation | Campestre, C.,Agamennone, M.,Tortorella, P.,Preziuso, S.,Biasone, A.,Gavuzzo, E.,Pochetti, G.,Mazza, F.,Hiller, O.,Tschesche, H.,Consalvi, V.,Gallina, C. N-Hydroxyurea as zinc binding group in matrix metalloproteinase inhibition: Mode of binding in a complex with MMP-8. Bioorg.Med.Chem.Lett., 16:20-24, 2006 Cited by PubMed: 16242329DOI: 10.1016/j.bmcl.2005.09.057 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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