1ZMY

cAbBCII-10 VHH framework with CDR loops of cAbLys3 grafted on it and in complex with hen egg white lysozyme

Summary for 1ZMY

• Entry DOI: 10.2210/pdb1zmy/pdb
• Related: 1JTO 1JTP 1JTT 1MEL
• Descriptor: Antibody cabbcII-10:lys3, Lysozyme C (3 entities in total)
• Functional Keywords: vhh; antibody; immune system; cdr grafting, immune system-hydrolase complex, immune system/hydrolase
• Biological source: Camelus dromedarius (Arabian camel); More
• Cellular location: Secreted: P00698
• Total number of polymer chains: 3
• Total formula weight: 43877.04

Authors

Saerens, D.,Pellis, M.,Loris, R.,Pardon, E.,Dumoulin, M.,Matagne, A.,Wyns, L.,Muyldermans, S.,Conrath, K. (deposition date: 2005-05-11, release date: 2005-10-04, Last modification date: 2011-07-13)

• Primary citation: Saerens, D.,Pellis, M.,Loris, R.,Pardon, E.,Dumoulin, M.,Matagne, A.,Wyns, L.,Muyldermans, S.,Conrath, K.; Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies; J.Mol.Biol., 352:597-607, 2005; PubMed: 16095608; DOI: 10.1016/j.jmb.2005.07.038

Experimental method

X-RAY DIFFRACTION (3 Å)