1YRY
Crystal structure of human PNP complexed with MESG
Summary for 1YRY
Entry DOI | 10.2210/pdb1yry/pdb |
Descriptor | Purine nucleoside phosphorylase, SULFATE ION, 7-METHYL-6-THIO-GUANOSINE, ... (4 entities in total) |
Functional Keywords | purine nucleoside phosphorylase, drug design, synchrotron, mesg, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytoskeleton (By similarity): P00491 |
Total number of polymer chains | 1 |
Total formula weight | 32786.40 |
Authors | Silva, R.G.,Pereira, J.H.,Canduri, F.,Basso, L.A.,de Azevedo Jr., W.F.,Santos, D.S. (deposition date: 2005-02-05, release date: 2006-01-17, Last modification date: 2023-10-25) |
Primary citation | Silva, R.G.,Pereira, J.H.,Canduri, F.,de Azevedo Jr., W.F.,Basso, L.A.,Santos, D.S. Kinetics and crystal structure of human purine nucleoside phosphorylase in complex with 7-methyl-6-thio-guanosine Arch.Biochem.Biophys., 442:49-58, 2005 Cited by PubMed: 16154528DOI: 10.1016/j.abb.2005.07.021 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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