1YER
HUMAN HSP90 GELDANAMYCIN-BINDING DOMAIN, "CLOSED" CONFORMATION
Summary for 1YER
Entry DOI | 10.2210/pdb1yer/pdb |
Descriptor | HEAT SHOCK PROTEIN 90 (2 entities in total) |
Functional Keywords | chaperone protein, geldanamycin, signal transduction, heat shock |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P07900 |
Total number of polymer chains | 1 |
Total formula weight | 25670.79 |
Authors | Stebbins, C.E.,Russo, A.A.,Pavletich, N.P. (deposition date: 1997-03-25, release date: 1998-04-22, Last modification date: 2024-02-14) |
Primary citation | Stebbins, C.E.,Russo, A.A.,Schneider, C.,Rosen, N.,Hartl, F.U.,Pavletich, N.P. Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent. Cell(Cambridge,Mass.), 89:239-250, 1997 Cited by PubMed: 9108479DOI: 10.1016/S0092-8674(00)80203-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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