1YAH
Crystal Structure of Human Liver Carboxylesterase complexed to Etyl Acetate; A Fatty Acid Ethyl Ester Analogue
Summary for 1YAH
Entry DOI | 10.2210/pdb1yah/pdb |
Related | 1MX1 1MX5 1MX9 1ya4 1ya8 1yaj |
Descriptor | CES1 protein, 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid, ... (6 entities in total) |
Functional Keywords | hydrolase, carboxylesterase, ethyl acetate, fatty acid acyl ester |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 3 |
Total formula weight | 178713.12 |
Authors | Fleming, C.D.,Bencahrit, S.,Edwards, C.C.,Hyatt, J.L.,Morton, C.L.,Howard-Williams, E.L.,Potter, P.M.,Redinbo, M.R. (deposition date: 2004-12-17, release date: 2005-08-02, Last modification date: 2023-08-23) |
Primary citation | Fleming, C.D.,Bencharit, S.,Edwards, C.C.,Hyatt, J.L.,Tsurkan, L.,Bai, F.,Fraga, C.,Morton, C.L.,Howard-Williams, E.L.,Potter, P.M.,Redinbo, M.R. Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil. J.Mol.Biol., 352:165-177, 2005 Cited by PubMed: 16081098DOI: 10.1016/j.jmb.2005.07.016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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