1Y98

Structure of the BRCT repeats of BRCA1 bound to a CtIP phosphopeptide.

Summary for 1Y98

• Entry DOI: 10.2210/pdb1y98/pdb
• Related: 1T15 1T29
• Descriptor: Breast cancer type 1 susceptibility protein, CtIP PHOSPHORYLATED PEPTIDE, COBALT (II) ION, ... (5 entities in total)
• Functional Keywords: breast cancer, brct, brca1, ctip, phosphopeptide, antitumor protein
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus. Isoform 3: Cytoplasm. Isoform 5: Cytoplasm: P38398
• Total number of polymer chains: 2
• Total formula weight: 25985.58

Authors

Varma, A.K.,Brown, R.S.,Birrane, G.,Ladias, J.A.A. (deposition date: 2004-12-14, release date: 2005-08-30, Last modification date: 2023-08-23)

• Primary citation: Varma, A.K.,Brown, R.S.,Birrane, G.,Ladias, J.A.A.; Structural Basis for Cell Cycle Checkpoint Control by the BRCA1-CtIP Complex.; Biochemistry, 44:10941-10946, 2005; PubMed: 16101277; DOI: 10.1021/bi0509651

Experimental method

X-RAY DIFFRACTION (2.5 Å)