1Y98
Structure of the BRCT repeats of BRCA1 bound to a CtIP phosphopeptide.
Summary for 1Y98
Entry DOI | 10.2210/pdb1y98/pdb |
Related | 1T15 1T29 |
Descriptor | Breast cancer type 1 susceptibility protein, CtIP PHOSPHORYLATED PEPTIDE, COBALT (II) ION, ... (5 entities in total) |
Functional Keywords | breast cancer, brct, brca1, ctip, phosphopeptide, antitumor protein |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus. Isoform 3: Cytoplasm. Isoform 5: Cytoplasm: P38398 |
Total number of polymer chains | 2 |
Total formula weight | 25985.58 |
Authors | Varma, A.K.,Brown, R.S.,Birrane, G.,Ladias, J.A.A. (deposition date: 2004-12-14, release date: 2005-08-30, Last modification date: 2023-08-23) |
Primary citation | Varma, A.K.,Brown, R.S.,Birrane, G.,Ladias, J.A.A. Structural Basis for Cell Cycle Checkpoint Control by the BRCA1-CtIP Complex. Biochemistry, 44:10941-10946, 2005 Cited by PubMed: 16101277DOI: 10.1021/bi0509651 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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