1Y4C

Designed Helical Protein fusion MBP

Summary for 1Y4C

• Entry DOI: 10.2210/pdb1y4c/pdb
• Related: 4HB1
• Related PRD ID: PRD_900001
• Descriptor: Maltose binding protein fused with designed helical protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose (3 entities in total)
• Functional Keywords: de novo designed helical protein, maltose binding protein fusion, de novo protein
• Biological source: Escherichia coli
• Cellular location: Periplasm: P02928
• Total number of polymer chains: 1
• Total formula weight: 54631.48

Authors

LaPorte, S.L.,Forsyth, C.M.,Cunningham, B.C.,Miercke, L.J.,Akhavan, D.,Stroud, R.M. (deposition date: 2004-11-30, release date: 2005-02-15, Last modification date: 2024-02-14)

• Primary citation: LaPorte, S.L.,Forsyth, C.M.,Cunningham, B.C.,Miercke, L.J.,Akhavan, D.,Stroud, R.M.; De novo design of an IL-4 antagonist and its structure at 1.9 A.; Proc.Natl.Acad.Sci.Usa, 102:1889-1894, 2005; PubMed: 15684085; DOI: 10.1073/pnas.0408890102

Experimental method

X-RAY DIFFRACTION (1.9 Å)