1WUA
The structure of Aplyronine A-actin complex
Summary for 1WUA
Entry DOI | 10.2210/pdb1wua/pdb |
Descriptor | Actin, alpha skeletal muscle, CALCIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | aplyronine a, macrolide, potent antitumor effect, marine sponge, structural protein |
Biological source | Oryctolagus cuniculus (rabbit) |
Cellular location | Cytoplasm, cytoskeleton: P68135 |
Total number of polymer chains | 1 |
Total formula weight | 43499.34 |
Authors | Hirata, K.,Muraoka, S.,Suenaga, K.,Kuroda, T.,Kato, K.,Tanaka, H.,Yamamoto, M.,Takata, M.,Yamada, K.,Kigoshi, H. (deposition date: 2004-12-03, release date: 2006-02-14, Last modification date: 2023-10-25) |
Primary citation | Hirata, K.,Muraoka, S.,Suenaga, K.,Kuroda, T.,Kato, K.,Tanaka, H.,Yamamoto, M.,Takata, M.,Yamada, K.,Kigoshi, H. Structure basis for antitumor effect of aplyronine a J.Mol.Biol., 356:945-954, 2006 Cited by PubMed: 16406066DOI: 10.1016/j.jmb.2005.12.031 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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