1WQV

Human Factor Viia-Tissue Factor Complexed with propylsulfonamide-D-Thr-Met-p-aminobenzamidine

Summary for 1WQV

• Entry DOI: 10.2210/pdb1wqv/pdb
• Descriptor: Coagulation factor VII, Tissue factor, beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: serine protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 71480.38

Authors

Kadono, S.,Sakamoto, A.,Kikuchi, Y.,Oh-eda, M.,Yabuta, N.,Koga, T.,Hattori, K.,Shiraishi, T.,Haramura, M.,Kodama, H. (deposition date: 2004-10-02, release date: 2005-10-02, Last modification date: 2023-11-15)

• Primary citation: Kadono, S.,Sakamoto, A.,Kikuchi, Y.,Oh-eda, M.,Yabuta, N.,Koga, T.,Hattori, K.,Shiraishi, T.,Haramura, M.,Kodama, H.,Esaki, T.,Sato, H.,Watanabe, Y.,Itoh, S.,Ohta, M.,Kozono, T.; Crystal structure of human factor VIIa/tissue factor in complex with peptide mimetic inhibitor; Biochem.Biophys.Res.Commun., 324:1227-1233, 2004; PubMed: 15504346; DOI: 10.1016/j.bbrc.2004.09.182

Experimental method

X-RAY DIFFRACTION (2.5 Å)